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Research Studies

Mental Health

The GLAD Study

Depression and anxiety are the most common mental health disorders worldwide. In the UK, 1 in 3 people will experience symptoms during their lifetime. The GLAD Study aims to better understand depression and anxiety in order to find effective treatments and improve the lives of people experiencing these disorders. A database of 50,000 people is being developed.

Genetic Links to Anxiety and Depression Study – GLAD Study  (Ends 30/11/2024)

IBPI (Integrated Bipolar Parenting Intervention)

This study is assessing how online parenting support specifically for parents diagnosed with bipolar disorder can improve both parents’ and children’s wellbeing.

Click here to register your interest https://forms.office.com/e/DXAnBvtneZ   (Ends 30/09/2024)

DIAMONDS

The overall aim of this project is to develop and test a bespoke educational package to help people with severe mental illness and diabetes to manage their diabetes better. We also want to explore how this approach can be adapted for other long-term conditions.

www.york.ac.uk/healthsciences/research/mental-health/projects/diamonds/   (Ends 24/05/2024)

EDGI

This study is the UK’s largest ever research project on eating disorders. Our aim is to collect the psychological, medical, and genetic information of 10,000 people with experience of any eating disorder. This will help us to better understand the role both our genes and environment play in the development of these illnesses.

edgiuk.org/about/  (Ends 01/09/2024)

Thoughts about physical activity: questionnaire study

Many people who experience psychosis spend too much time sitting down and not enough time exercising. The study aims to understand people’s thoughts about physical activity in order to develop and validate four new questionnaires to assess this. The study also aims to test whether these thoughts are predicted by a number of psychological or physical health factors.

(Ends 01/04/2024) No longer open to recruitment, study in follow up.

RADAR follow up study

Livewell previously took part in a randomised controlled trial exploring what happens to people who reduce and come off their antipsychotic medication gradually with support from their doctor, compared to people who stay on it. In the current study, we want to understand how things turn out in the long-run. In order to do this, we will to follow-up the people enrolled in the RADAR study a few years later to see how they are doing in the long-run.

(Ends 31/03/2024)

STOP (Successful Treatment of Paranoia)

Paranoia can be one of the most disabling psychological experiences. It can cause distress, other mental health problems, and problems in work, family, and social situations. The purpose of the STOP study is to investigate the effects of a mobile phone App to help people manage feelings of paranoia in a way that is less distressing and disruptive to their lives.

(Ends 31/08/2024)

Parkinsons

TOPHAT

The aim of the research is to see whether ondansetron will effectively treat visual hallucinations in people with Parkinson’s or Lewy Body Dementia (LBD). As this is an already licensed drug, if the research shows significant outcomes, ondansetron could be available soon for people with Parkinson’s or LBD who experience hallucinations.

www.parkinsons.org.uk/research/tophat-trial-ondansetron-parkinsons-hallucination-treatment   (Ends 01/01/2024)

Parkinsons Families Project (PFP)

The aim of the study is to identify new genes that predispose or cause Parkinson’s Disease or Parkinsonism. We are particularly interested in studying the genetic makeup of two groups of people:

  1. those who developed Parkinson’s before the age of 45; and
  2. those who have a family history of other relatives affected by Parkinson’s or other movement disorders.

Parkinson’s Family Projects :: Home (parkinsonsfamiliesprojects.com)  (Ends 01/01/2030)

OBtAIN

Evaluating the Occupation-Based Complex Intervention for living well with anxiety and Parkinson’s Disease. Our colleagues in University of Plymouth are working with our Occupational Therapy Teams to recruit suitable participants.

(Ends 31/10/2023) No longer open to recruitment, study in follow up.

Here are some of the team of Occupational Therapists in Tavistock that are running the study:

Stroke

PLORAS

Predicting Language Outcome and Recovery After Stroke. This invites people who have had a stroke at any time to undertake language assessments and reviews their brain scans.

www.ucl.ac.uk/ploras/   (Ends 20/08/2027)

Parkinsons & Dementia

CoCoA 

Computerised cognitive assessments in neurodegenerative disorders, This study seeks to find the best way of diagnosing and assessing for Dementia and other Neurodegenerative disorders.

Contact the Livewell research team.  (Ends 01/01/2025)

Dementia

Time for Dementia

The Time for Dementia programme gives undergraduate healthcare students the unique opportunity to regularly meet with a person with dementia and their carer. The students can get to know the person and the carer outside of a clinical setting. Regular meetings help trainee healthcare professionals understand what it’s really like to live with dementia.

Time for Dementia programme | Alzheimer’s Society (alzheimers.org.uk)   (Ends 30/11/2024)

Learning Disabilities

PETAL 

This is a national study that aims to develop and test a PErsonalised Treatment package for Adults with Learning disability who display aggressive challenging behaviour (PETAL). Aggression in adults with learning disability is common and persistent over time. Moderate to severe aggression is considered a public health problem. It is a major reason for emergency care and admission to psychiatric hospitals and can significantly reduce the mental, physical wellbeing and overall quality of life of the individual and their family/paid carers. The PETAL therapy aims to develop a personalised multicomponent approach to explore the response of adults with learning disability who display aggression to the PETAL therapy alongside usual care compared to usual care alone in the NHS.

The PETAL Programme | Psychiatry – UCL – University College London   (Ends Sept 2025)

Tissue Viability

Venus6

The VenUS-6 trial will compare evidence based compression (choice of four-layer bandage or two-layer compression hosiery), two-layer bandage or adjustable hook-and-loop fastened compression systems (“compression wraps”), to see if these make any difference to how quickly venous leg ulcers heal. To run this study we have set up our first research clinic space to see suitable patients from our tissue viability service.

VENUS-6 – Health Sciences, University of York   (Ends 30/04/2024)

Promise 2 (Intelligent Sensing to Promote Self-Management of Posture and Mobility)

Pressure Ulcers (PUs) represent a major burden to populations worldwide and have been attributed with the highest disability index for dermatological conditions. In 2017-2021 PROMISE was conducted across four community NHS Trusts, involving 100 patients. Following the completion of PROMISE (2021) all four community trusts have continued to implement CPM in their practice of pressure ulcer prevention. This follow up study will conduct a realist synthesis and evaluation in the community to develop a programme theory to explain how CPM works, for whom, under what circumstances, how and why?

(Ends 31/08/2024)

COVID

STIMULATE (Symptoms, Trajectory, Inequalities and Management: Understanding Long-COVID to Address and Transform Existing Integrated Care Pathways)

Long COVID affects over a million people in the UK, with wide-ranging disabling symptoms. We need to better understand, diagnose, and treat this new disease. To do this effectively we need to join up services including specialists, hospitals, and community care, creating a care pathway

This will be the largest clinical study of long COVID to-date over two years.

https://www.stimulate-icp.org/ (Ends 31/07/2024)

Coming soon…

Check back soon to find out about upcoming studies.